GCU NUR 641E Topic 5: Cardiovascular System And Lymphatic System: Selected Pathophysiology And Pharmacologic Therapy

Mar 31-Apr 6, 2022

Max Points:130

Objectives:

Describe normal pathophysiology and alterations in the cardiovascular system and lymphatic system.
Integrate knowledge of pathophysiology and pharmacology into teaching and educational materials in diverse settings.
Describe a pharmacological intervention using an evidence-based treatment guideline.

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GCU NUR 641E Topic 5: Cardiovascular System And Lymphatic System: Selected Pathophysiology And Pharmacologic Therapy — Topic 5 DQ 1

Mar 31-Apr 2, 2022

Choose a medical condition from the cardiovascular system and lymphatic system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Make sure that you select a different medical condition than your peers. Include the name of the medical condition in the subject line so that the medical condition can be followed. Include your references in APA style.

REPLY TO DISCUSSION

Nicole

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Replies to Nicole Santos

ORTHOSTATIC (POSTURAL) HYPOTENSION

Orthostatic hypotension, or postural hypotension, refers to a decrease of 20 mmHg in systolic blood pressure, and a decrease of 10 mmHg in diastolic blood pressure within a period of 3 minutes when moving from a supine, to sitting, to standing position. Primary orthostatic hypotension is typically called neurogenic hypotension, which is a result of a neurologic disorder that affects the autonomic system. This increases sympathetic activity through baroreceptors in the carotid sinus and aortic arch which prompts the increase in heart rate and constriction of systemic arteries that maintain stable blood pressure, which is not the case in individuals with orthostatic hypotension.

This disease is more common in older adults due to the slowing of postural reflexes as part of normal aging and other neurologic diseases like Parkinson and multiple system atrophy. Some patient education related to this order would be to change positions slowly to reduce light headedness and falls, drinking plenty of water, avoid crossing legs while sitting, and elevating the head of the bed.

Reference

McCance, K. L., Huether, S. E., Brashers, V. L., Rote, N. S., & McCance, K. L. (2019). Pathophysiology: The biologic basis for disease in adults and children

Topic 5 DQ 2

Mar 31-Apr 4, 2022

Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.

REPLY TO DISCUSSION

Vanessa

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Replies to Vanessa Brown

Ketoprofen

Traditionally, lymphedema would be treated with compression garments, lymphatic massage, or surgical procedures. The treatment for lymphedema has not really included medication therapy, but there have been trials that have shown promising results with the NSAID ketoprofen (Rockson et al., 2018). The mechanism of action for ketoprofen is that of dual inflammatory inhibition pathways that blocks both cyclooxygenase (COX) and 5-LO (Rockson et al., 2018). The inhibition of 5-LO then negatively effects leukotriene B4 (LTB4) production. The intended results from the use of ketoprofen was to reduce swelling,relieve pain, and improve the skin thickening that accompanies lymphedema. When taking this medication, monitoring of blood work will be needed with extended use to evaluate for toxicity, especially in high-risk patients (Drugs.com, n.d.). Monitoring for other dangerous adverse effects from ketoprofen should also be done. These include severe allergic reaction, possible heart attack or stroke, or gastrointestinal bleeding (Drugs.com, n.d.). Some of the common side effects of this NSAID are heartburn, gas, nausea, vomiting, diarrhea, constipation, and dizziness (Drugs.com, n.d.). Some possible drug interactions are easier bruising and bleeding with certain antidepressants, increased effect of anticoagulants, and GI issues with steroid medications (Drugs.com, n.d.).

References

Drugs.com. (n.d.). Ketoprofen. https://www.drugs.com/mtm/ketoprofen.html

Rockson, S. G., Tian, W., Jiang, X., Kuznetsova, T., Haddad, F., Zampell, J., Mehrara, B., Sampson, J. P., Roche, L., Kim, J., & Nicolls, M. R. (2018). Pilot studies demonstrate the potential benefits of anti-inflammatory therapy in human lymphedema. JCI Insight, 3(20). https://doi.org/10.1172/jci.insight.123775

GCU NUR 641E Topic 5: Cardiovascular System And Lymphatic System: Selected Pathophysiology And Pharmacologic Therapy — Topic 6 CLC – Staff Training

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Start Date

Apr 7, 2022, 12:00 AM

Due Date

Apr 13, 2022, 11:59 PM

Points

176

Rubric

View Rubric

Status

Published

Assessment Traits

Group

Requires Lopeswrite

Assessment Description

This is a Collaborative Learning Community (CLC) assignment.

This assignment requires completion of two parts: a presentation and an educational resource.

Part 1: Presentation

Create a PowerPoint presentation (15-20 slides, with speaker notes) for a staff training meeting on the pathophysiology and pharmacologic agents for a select disease process.

Each CLC will choose one disease process from the following list and obtain instructor approval to avoid duplication:

Alzheimer’s Disease
Asthma
Diabetes Type 2
Epilepsy
Gastroesophageal Reflux Disease (GERD)
Hypertension
Hypothyroidism
Multiple Sclerosis
Peptic Ulcer Disease
Tuberculosis

Describe the physiology and pathophysiology of the disease, clinical manifestations, and evaluation (e.g., labs, imaging).

Describe the pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics, drug interactions, side effects, adverse reactions, and application of the nursing process in monitoring the drug therapy.

Part 2: Educational Resource

Using your selected disease process from Part 1, develop an educational resource that can assist staff in increasing patient knowledge of medications and medication compliance.

The vehicle for your educational resource could include pamphlets, handouts, or any other brief, concise medium to convey the information to staff.

General Requirements

Refer to the resource, “Creating Effective PowerPoint Presentations,” located in the Student Success Center, for additional guidance on completing this assignment in the appropriate style.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. A link to the LopesWrite technical support articles is located in Class Resources if you need assistance.

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CLC – Staff Training – Rubric

Collapse All CLC – Staff Training – RubricCollapse All

Physiology and Pathophysiology

26.4 points

Criteria Description

Physiology and Pathophysiology

5: Excellent 93-100%

26.4 points

A description of physiology and pathophysiology of the disease, clinical manifestations, and evaluation is present. Supporting material is of exceptional quality and quantity.

4: Good 89-92%

24.29 points

A description of physiology and pathophysiology of the disease, clinical manifestations, and evaluation is presented. Supporting material is of above average quality and quantity.

3: Satisfactory 81-88%

23.23 points

A description of physiology and pathophysiology of the disease, clinical manifestations, and evaluation is adequately presented.

2: Less Than Satisfactory 76-80%

21.12 points

A description of physiology and pathophysiology of the disease, clinical manifestations, and evaluation is present, but incomplete or inaccurate.

1: Unsatisfactory 0-75%

0 points

A description of physiology and pathophysiology of the disease, clinical manifestations, and evaluation is not present.

Pharmacologic Treatment

26.4 points

Criteria Description

Pharmacologic Treatment

5: Excellent 93-100%

26.4 points

A description of pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics, drug interactions, side effects, adverse reactions, and application of the nursing process in monitoring drug therapy is presented in a thoughtful and insightful manner. Supporting material is of exceptional quality and quantity.

4: Good 89-92%

24.29 points

A description of pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics, drug interactions, side effects, adverse reactions, and application of the nursing process in monitoring drug therapy is adequately presented. Supporting material is of above average quality and quantity. GCU NUR 641E Topic 5: Cardiovascular System And Lymphatic System: Selected Pathophysiology And Pharmacologic Therapy

3: Satisfactory 81-88%

23.23 points

A description of pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics, drug interactions, side effects, adverse reactions, and application of the nursing process in monitoring drug therapy is adequately presented. Supporting material is of baseline acceptable quality and quantity.

2: Less Than Satisfactory 76-80%

21.12 points

1: Unsatisfactory 0-75%

0 points

Educational Resource

26.4 points

Criteria Description

Educational Resource

5: Excellent 93-100%

26.4 points

An educational resource that can assist staff in increasing patient knowledge of medications and medication compliance is presented in a thoughtful and insightful manner. Supporting material is of exceptional quality and quantity.

4: Good 89-92%

24.29 points

An educational resource that can assist staff in increasing patient knowledge of medications and medication compliance is adequately presented. Supporting material is of above average quality and quantity.

3: Satisfactory 81-88%

23.23 points

An educational resource that can assist staff in increasing patient knowledge of medications and medication compliance is adequately presented. Supporting material is of baseline acceptable quality and quantity.

2: Less Than Satisfactory 76-80%

21.12 points

An educational resource that can assist staff in increasing patient knowledge of medications and medication compliance is present, but incomplete or inaccurate.

1: Unsatisfactory 0-75%

0 points

An educational resource that can assist staff in increasing patient knowledge of medications and medication compliance is not present.

Presentation of Content

26.4 points

Criteria Description

Presentation of Content

5: Excellent 93-100%

26.4 points

The content is written clearly and concisely. Ideas universally progress and relate to each other. The project includes motivating questions and advanced organizers. The project gives the audience a clear sense of the main idea.

4: Good 89-92%

24.29 points

The content is written with a logical progression of ideas and supporting information exhibiting a unity, coherence, and cohesiveness. Includes persuasive information from reliable sources.

3: Satisfactory 81-88%

23.23 points

The presentation slides are generally competent, but ideas may show some inconsistency in organization or in their relationships to each other.

2: Less Than Satisfactory 76-80%

21.12 points

The content is vague in conveying a point of view and does not create a strong sense of purpose. Includes some persuasive information.

1: Unsatisfactory 0-75%

0 points

The content lacks a clear point of view and logical sequence of information. Includes little persuasive information. Sequencing of ideas is unclear.

Layout

26.4 points

Criteria Description

Layout

5: Excellent 93-100%

26.4 points

The layout is visually pleasing and contributes to the overall message with appropriate use of headings, subheadings, and white space. Text is appropriate in length for the target audience and to the point. The background and colors enhance the readability of the text.

4: Good 89-92%

24.29 points

The layout background and text complement each other and enable the content to be easily read. The fonts are easy to read and point size varies appropriately for headings and text.

3: Satisfactory 81-88%

23.23 points

The layout uses horizontal and vertical white space appropriately. Sometimes the fonts are easy to read, but in a few places the use of fonts, italics, bold, long paragraphs, color, or busy background detracts and does not enhance readability.

2: Less Than Satisfactory 76-80%

21.12 points

The layout shows some structure, but appears cluttered and busy or distracting with large gaps of white space or a distracting background. Overall readability is difficult due to lengthy paragraphs, too many different fonts, dark or busy background, overuse of bold, or lack of appropriate indentations of text.

1: Unsatisfactory 0-75%

0 points

The layout is cluttered, confusing, and does not use spacing, headings, and subheadings to enhance the readability. The text is extremely difficult to read with long blocks of text, small point size for fonts, and inappropriate contrasting colors. Poor use of headings, subheadings, indentations, or bold formatting is evident.

Language Use and Audience Awareness (includes sentence construction, word choice, etc.)

8.8 points

Criteria Description

Language Use and Audience Awareness (includes sentence construction, word choice, etc.)

5: Excellent 93-100%

8.8 points

The writer uses a variety of sentence constructions, figures of speech, and word choice in distinctive and creative ways that are appropriate to purpose, discipline, and scope.

4: Good 89-92%

8.1 points

The writer is clearly aware of audience, uses a variety of appropriate vocabulary for the targeted audience, and uses figures of speech to communicate clearly.

3: Satisfactory 81-88%

7.74 points

Language is appropriate to the targeted audience for the most part.

2: Less Than Satisfactory 76-80%

7.04 points

Some distracting inconsistencies in language choice (register) or word choice are present. The writer exhibits some lack of control in using figures of speech appropriately.

1: Unsatisfactory 0-75%

0 points

Inappropriate word choice and lack of variety in language use are evident. Writer appears to be unaware of audience. Use of primer prose indicates writer either does not apply figures of speech or uses them inappropriately.

Mechanics of Writing (includes spelling, punctuation, grammar, language use)

17.6 points

Criteria Description

Mechanics of Writing (includes spelling, punctuation, grammar, language use)

5: Excellent 93-100%

17.6 points

Writer is clearly in control of standard, written, academic English.

4: Good 89-92%

16.19 points

Slides are largely free of mechanical errors, although a few may be present.

3: Satisfactory 81-88%

15.49 points

Some mechanical errors or typos are present, but they are not overly distracting to the reader.

2: Less Than Satisfactory 76-80%

14.08 points

Frequent and repetitive mechanical errors distract the reader.

1: Unsatisfactory 0-75%

0 points

Slide errors are pervasive enough that they impede communication of meaning.

Documentation of Sources

17.6 points

Criteria Description

Documentation of Sources (citations, footnotes, references, bibliography, etc., as appropriate to assignment and style)

5: Excellent 93-100%

17.6 points

Sources are completely and correctly documented, as appropriate to assignment and style, and format is free of error.

4: Good 89-92%

16.19 points

Sources are documented, as appropriate to assignment and style, and format is mostly correct.

3: Satisfactory 81-88%

15.49 points

Sources are documented, as appropriate to assignment and style, although some formatting errors may be present.

2: Less Than Satisfactory 76-80%

14.08 points

Documentation of sources is inconsistent or incorrect, as appropriate to assignment and style, with numerous formatting errors.

1: Unsatisfactory 0-75%

0 points

Sources are not documented.