Antidepressant Medications on Neurotransmitters Paper

Based on what is known about the role of dopamine, serotonin, and norepinephrine in mood, each seems a likely target for effective depression treatment. In addition, targeting more than one at a time might show a marked increase in depression treatment effectiveness. In reality, more does not appear to be better. Several major pharmaceutical companies developed triple reuptake inhibitors and tested them with little success.

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The three neurotransmitter systems that are involved in depression are serotonin, norepinephrine, and dopamine. As such, a medication that targets all three should be the most effective for treating depression. In reality, the triple reuptake inhibitor does not work to treat depression.

For this Assignment, research at least three peer-reviewed articles that examine the effects of antidepressant medications on neurotransmitters and the body. In addition, examine the side effects of antidepressants.

Submit by Day 7 a 2- to 3-page paper that analyzes why the triple reuptake inhibitor might not work to treat depression. In your analysis, be sure to address each of the neurotransmitters as well as potential side effects.

Support your Assignment with specific references to the Learning Resources and any additional references you used.

READINGS

Advokat, C. D., & Comaty, J. E., & Julien, R. M. (2019). Julien’s primer of drug action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (14th ed.). New York, NY: Worth Publishers/Macmillan.
- Chapter 12, “Antidepressant Drugs” (pp. 433-478)

Lichtblau, L. (2011). Psychopharmacology demystified (1st ed.). Clifton Park, NY: Delmar/Cengage Learning.
- Chapter 2, “Pharmacotherapy of Depression” (pp. 21–36)
Hancock, S. D, & McKim, W. A. (2018). Drugs and behavior: An introduction to behavioral pharmacology (8th ed.). Upper Saddle River, NJ: Pearson.
- Chapter 13, “Antidepressants” (pp. 291-306)

Niv, N., Shatkin, J., Hamilton, A., Unützer, J., Klap, R., & Young, A. (2010). The Use of Herbal Medications and Dietary Supplements by People with Mental Illness. Community Mental Health Journal, 46(6), 563-569. Retrieved from the Walden Library databases.
Spinella, M. (2001). The psychopharmacology of herbal medicine: Plant drugs that alter mind, brain, and behavior. Cambridge, MA: MIT Press.
- Chapter 7, “Psychotherapeutic Herbs” (pp. 233–240 & 243–273)
U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health. (2013, March). Depression.Retrieved from http://www.nimh.nih.gov/health/topics/depression/index.shtml
White, K. P. (2009). What psychologists should know about homeopathy, nutrition, and botanical medicine. Professional Psychology: Research And Practice, 40(6), 633-640. Retrieved from the Walden Library databases.

Support your Assignment with specific references to the Learning Resources and any additional references you used.